{"id":73,"date":"2016-02-15T12:15:54","date_gmt":"2016-02-15T11:15:54","guid":{"rendered":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/?page_id=73"},"modified":"2025-01-23T09:27:33","modified_gmt":"2025-01-23T08:27:33","slug":"publications","status":"publish","type":"page","link":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/?page_id=73&lang=en","title":{"rendered":"Publications"},"content":{"rendered":"\t\t
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Cannone G, Berto L, Malhaire F, Ferguson G, Fouillen A, Balor S, Font-Ingles J, Llebaria A, Goudet C, Kotecha A, K R V, Lebon G. Conformational diversity in class C GPCR positive allosteric modulation.<\/em><\/span> Nat Commun.<\/strong> 2025 Jan 13;16(1):619. doi: 10.1038\/s41467-024-55439-9.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr><\/tbody><\/table><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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Ribeiro EA Jr, Leyrat C, G\u00e9rard FCA, Jamin M. Dimerization of Rabies Virus Phosphoprotein and Phosphorylation of Its Nucleoprotein Enhance Their Binding Affinity.<\/span> <\/em>Viruses.<\/strong> 2024 Nov 4;16(11):1735. doi: 10.3390\/v16111735.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>

Fouillen A, Couvineau P, Gaibelet G, Rich\u00e9 S, Orcel H, Mendre C, Kanso A, Lanotte R, Nguyen J, Dimon J, Urbach S, Sounier R, Granier S, Bonnet D, Cong X, Mouillac B, D\u00e9m\u00e9n\u00e9 H. Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies.<\/span><\/em> Comput Struct Biotechnol J.<\/strong> 2024 Oct 24;23:3784-3799. doi: 10.1016\/j.csbj.2024.10.039.<\/span><\/p><\/td>

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Diagouraga B, Tambones I, Carivenc C, Bechara C, Nadal M, de Massy B, le Maire A, Robert T. The TOPOVIBL meiotic DSB formation protein: new insights from its biochemical and structural characterization.<\/span><\/em> Nucleic Acids Res.<\/strong> 2024 Aug 27;52(15):8930-8946. doi: 10.1093\/nar\/gkae587.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Stanajic-Petrovic G, Keck M, Barbe P, Urman A, Correia E, Isnard P, Duong Van Huyen JP, Chmeis K, Diarra SS, Palea S, Theodoro F, Nguyen AL, Castelli F, Pruvost A, Zhao W, Mendre C, Mouillac B, Bienaim\u00e9 F, Robin P, Kessler P, Llorens-Cortes C, Servent D, Nozach H, Maill\u00e8re B, Guo D, Truillet C, Gilles N. A Snake Toxin Derivative for Treatment of Hyponatremia and Polycystic Kidney Diseases.<\/span> <\/em>J Am Soc Nephrol.<\/strong> 2024 Oct 16. doi: 10.1681\/ASN.0000000505.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>

Drakopoulos A, Koszegi Z, Seier K, H\u00fcbner H, Maurel D, Sounier R, Granier S, Gmeiner P, Calebiro D, Decker M. Design, Synthesis, and Characterization of New \u03b4 Opioid Receptor-Selective Fluorescent Probes and Applications in Single-Molecule Microscopy of Wild-Type Receptors.<\/em><\/span> J Med Chem.<\/strong> 2024 Aug 8;67(15):12618-12631. doi: 10.1021\/acs.jmedchem.4c00627.<\/span><\/p><\/td>

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Khalfi P, Denis Z, McKellar J, Merolla G, Chavey C, Ursic-Bedoya J, Soppa L, Szirovicza L, Hetzel U, Dufourt J, Leyrat C, Goldmann N, Goto K, Verrier E, Baumert TF, Glebe D, Courgnaud V, Gregoire D, Hepojoki J, Majzoub K. Comparative analysis of human, rodent and snake deltavirus replication.<\/span><\/em> PLoS Pathog.<\/strong> 2024 Mar 5;20(3):e1012060. doi: 10.1371\/journal.ppat.1012060.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J, El\u00e9ou\u00ebt JF, Galloux M, Renner M. Structure of the N-RNA\/P interface indicates mode of L\/P recruitment to the nucleocapsid of human metapneumovirus.<\/span><\/em> Nat Commun.<\/strong> 2023 Nov 22;14(1):7627. doi: 10.1038\/s41467-023-43434-5.
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Otun O, Aljamous C, Del Nero E, Arimont-Segura M, Bosma R, Zarzycka B, Girbau T, Leyrat C, de Graaf C, Leurs R, Durroux T, Granier S, Cong X, Bechara C. Conformational dynamics underlying atypical chemokine receptor 3 activation.<\/em> <\/span>Proc Natl Acad Sci U S A.<\/strong>\u00a02024 Jul 23;121(30):e2404000121 doi:10.1073\/pnas.2404000121<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Healey RD, Couillaud L, Hoh F, Mouhand A, Fouillen A, Couvineau P, Granier S, Leyrat C. Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies.<\/em> <\/span>Commun Chem.<\/strong> 2023 Jul 28;6(1):160. doi: 10.1038\/s42004-023-00962-x.
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Fouillen A, Bous J, Granier S, Mouillac B, Sounier R. Bringing GPCR Structural Biology to Medical Applications: Insights from Both V2 Vasopressin and Mu-Opioid Receptors.<\/em><\/span> Membranes<\/strong> 2023 Jun 16;13(6):606. doi: 10.3390\/membranes13060606.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Erlandson SC, Rawson S, Osei-Owusu J, Brock KP, Liu X, Paulo JA, Mintseris J, Gygi SP, Marks DS, Cong X, Kruse AC. The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.<\/span><\/em> Nat Chem Biol.<\/strong> 2023 Apr 20. doi: 10.1038\/s41589-023-01321-6.
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Jobin ML, De Smedt-Peyrusse V, Ducrocq F, Baccouch R, Oummadi A, Pedersen MH, Medel-Lacruz B, Angelo MF, Villette S, Van Delft P, Fouillen L, Mongrand S, Selent J, Tolentino-Cortez T, Barreda-G\u00f3mez G, Gr\u00e9goire S, Masson E, Durroux T, Javitch JA, Guix\u00e0-Gonz\u00e1lez R, Alves ID, Trifilieff P. Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling.<\/span><\/em> Mol Psychiatry.<\/strong> 2023 May;28(5):1960-1969. doi: 10.1038\/s41380-022-01928-6. Erratum in: doi: 10.1038\/s41380-023-02196-8.
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Roy A, Chan Mine E, Gaifas L, Leyrat C, Volchkova VA, Baudin F, Martinez-Gil L, Volchkov VE, Karlin DG, Bourhis JM, Jamin M.\u00a0Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization.<\/span><\/em> Biomolecules.<\/strong> 2023 Mar 1;13(3):455. doi: 10.3390\/biom13030455.
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Bous J, Fouillen A, Orcel H, Granier S, Bron P, Mouillac B. Structures of the arginine-vasopressin and oxytocin receptor signaling complexes.<\/span><\/em> Vitam Horm.<\/strong> 2023;123:67-107. doi: 10.1016\/bs.vh.2022.12.003.
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Yu Y, Ma Z, Pacalon J, Xu L, Li W, Belloir C, Topin J, Briand L, Golebiowski J, Cong X. Extracellular loop 2 of G protein-coupled olfactory receptors is critical for odorant recognition.<\/span><\/em> J Biol Chem.<\/strong> 2022 Sep;298(9):102331. doi: 10.1016\/j.jbc.2022.102331.
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Xu R, Cong X, Zheng Q, Xu L, Ni MJ, de March CA, Matsunami H, Golebiowski J, Ma M, Yu Y. Interactions among key residues regulate mammalian odorant receptor trafficking<\/span>.<\/span> <\/em>FASEB J.<\/strong> 2022 Jul;36(7):e22384. doi: 10.1096\/fj.202200116RR.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W. Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex.<\/span><\/em>\u00a0Nat Commun.<\/strong> 2022 Nov 16;13(1):7010. doi: 10.1038\/s41467-022-34773-w.
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Lambey P, Otun O, Cong X, Hoh F, Brunel L, Verdi\u00e9 P, Grison CM, Peysson F, Jeannot S, Durroux T, Bechara C, Granier S, Leyrat C. Structural insights into recognition of chemokine receptors by<\/em> Staphylococcus aureus<\/i>\u00a0leukotoxins.<\/span> Elife<\/strong>. 2022 Mar 21;11:e72555. doi: 10.7554\/eLife.72555. PMID: 35311641; PMCID: PMC9005193.<\/span><\/td>PUBMED<\/a> <\/span><\/td><\/tr>
G\u00e9rard FCA, Bourhis JM, Mas C, Branchard A, Vu DD, Varhoshkova S, Leyrat C, Jamin M. Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module.<\/span><\/em> Viruses.<\/strong> 2022 Dec 16;14(12):2813. doi: 10.3390\/v14122813.
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Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P. Structure of the vasopressin hormone-V2 receptor-\u03b2-arrestin1 ternary complex.<\/em><\/span> Sci Adv.<\/strong> 2022 Sep 2;8(35):eabo7761. doi: 10.1126\/sciadv.abo7761<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Szalai L, Szir\u00e1ki A, Erd\u00e9lyi LS, Kov\u00e1cs KB, T\u00f3th M, T\u00f3th AD, Turu G, Bonnet D, Mouillac B, Hunyady L, Balla A. Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones.<\/span><\/em> Front Pharmacol.<\/strong> 2022 Jan 25;13:811836. doi: 10.3389\/fphar.2022.811836.
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Droctov\u00e9 L, Ciolek J, Mendre C, Chorfa A, Huerta P, Carvalho C, Gouin C, Lancien M, Stanajic-Petrovic G, Braco L, Blanchet G, Upert G, De Pauw G, Barbe P, Keck M, Mourier G, Mouillac B, Denis S, Rodr\u00edguez de la Vega RC, Quinton L, Gilles N. A new Kunitz-type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor.<\/span><\/em> Br J Pharmacol.<\/strong> 2022 Jul;179(13):3470-3481. doi: 10.1111\/bph.15814.
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Grison CM, Lambey P, Jeannot S, Del Nero E, Fontanel S, Peysson F, Heuninck J, Sounier R, Durroux T, Leyrat C, Granier S, Bechara C. Molecular insights into mechanism of GPCR hijacking by Staphylococcus aureus.<\/em> <\/span>Proc Natl Acad Sci USA.<\/strong> 2021 Oct 19;118(42):e2108856118. doi: 10.1073\/pnas.2108856118.<\/span><\/span><\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Healey RD, Basu S, Humm AS, Leyrat C, Cong X, Golebiowski J, Dupeux F, Pica A, Granier S, M\u00e1rquez JA. An automated platform for structural analysis of membrane proteins through serial crystallography.<\/em><\/span> Cell Rep Methods.<\/strong> 2021 Oct 25;1(6) doi: 10.1016\/j.crmeth.2021.100102.<\/span><\/td>PUBMED<\/a>\u00a0<\/span><\/td><\/tr>
Healey RD, Saied EM, Cong X, Karsai G, Gabeller L, Saint-Paul J, Del Nero E, Jeannot S, Drapeau M, Fontanel S, Maurel D, Basu S, Leyrat C, Golebiowski J, Bossis G, Bechara C, Hornemann T, Arenz C, Granier S.\u00a0<\/span>Discovery and mechanisms of action of small molecule inhibitors of ceramidases. <\/em><\/span>Angew Chem int Ed Engl.<\/strong> 2021 Oct 20: doi: 10.1002\/anie.202109967.\u00a0<\/span><\/span><\/td>PUBMED<\/a>\u00a0<\/span><\/td><\/tr>
Cong X, Maurel D, D\u00e9m\u00e9n\u00e9 H, Vasiliauskait\u00e9-Brooks I, Hagelberger J, Peysson F, Saint-Paul J, Golebiowski J, Granier S, Sounier R. Molecular insights into the biased signaling mechanism of the \u03bc-opioid receptor.<\/span><\/em> Mol Cell.<\/strong> 2021 Oct 21;81(20):4165-4175.e6. doi: 10.1016\/j.molcel.2021.07.033.<\/span><\/span><\/td>PUBMED<\/a>\u00a0<\/span><\/td><\/tr>
Dadouch M, Ladner Y, Bich C, Montels J, Morel J, Bechara C, Perrin C. In-capillary (electrophoretic) digestion-reduction-separation: A smart tool for middle-up analysis of mAb.<\/span><\/em> J Chromatogr A.<\/strong> 2021 Jul 5;1648:462213. doi: 10.1016\/j.chroma.2021.462213.
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Bous J, Orcel H, Floquet N, Leyrat C, Lai-Kee-Him J, Gaibelet G, Ancelin A, Saint-Paul J, Trapani S, Louet M, Sounier R, D\u00e9m\u00e9n\u00e9 H, Granier S, Bron P, Mouillac B.\u00a0Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.<\/em><\/span>\u00a0<\/span>Sci Adv.<\/strong>\u00a02021 May 21;7(21):eabg5628.<\/span><\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Lemel L, Nie\u015bcierowicz K, Garc\u00eda-Fern\u00e1ndez MD, Darr\u00e9 L, Durroux T, Busnelli M, Pezet M, Rebeille F, Jouhet J, Mouillac B, Domene C, Chini B, Cherezov V, Moreau CJ. The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules.<\/span><\/em>\u00a0J Lipid Res.<\/strong>\u00a02021 Feb 26:100059.<\/span><\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Aissaoui N, Lai-Kee-Him J, Mills A, Declerck N, Morichaud Z, Brodolin K, Baconnais S, Le Cam E, Charbonnier JB, Sounier R, Granier S, Ropars V, Bron P, Bellot G.\u00a0Modular Imaging Scaffold for Single-Particle Electron Microscopy.<\/span><\/em>\u00a0ACS Nano.<\/strong>\u00a02021 Mar 23;15(3):4186-4196.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Hus-Citharel A, Bouby N, Corbani M, Mion J, Mendre C, Darusi J, Tomboly C, Trueba M, Serradeil-Le Gal C, Llorens-Cortes C, Guillon G. Characterization of a functional V1B<\/sub>\u00a0vasopressin receptor in the male rat kidney: evidence for cross talk between V1B<\/sub>\u00a0and V2<\/sub> receptor signaling pathways<\/span><\/em>. Am J Physiol Renal Physiol.<\/strong> 2021 Sep 1;321(3):F305-F321. doi: 10.1152\/ajprenal.00081.2021.
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Droctov\u00e9 L, Lancien M, Tran VL, Susset M, Jego B, Theodoro F, Kessler P, Mourier G, Robin P, Diarra SS, Palea S, Flahault A, Chorfa A, Corbani M, Llorens-Cortes C, Mouillac B, Mendre C, Pruvost A, Servent D, Truillet C, Gilles N. A snake toxin as a theranostic agent for the type 2 vasopressin receptor.<\/em><\/span> Theranostics.<\/strong> 2020 Sep 18;10(25):11580-11594. doi: 10.7150\/thno.47485.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr>
Gentzsch C, Seier K, Drakopoulos A, Jobin ML, Lanoisel\u00e9e Y, Koszegi Z, Maurel D, Sounier R, H\u00fcbner H, Gmeiner P, Granier S, Calebiro D, Decker M.\u00a0Selective and Wash-Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single-Molecule Imaging of \u03bc-Opioid Receptor Dimerization.<\/span><\/em>\u00a0Angew Chem Int Ed Engl.<\/strong>\u00a02020 Apr 6;59(15):5958-5964.<\/span><\/td>PUBMED<\/a><\/span><\/td><\/tr><\/tbody><\/table><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t2019 - 2015<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t
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Ramanoudjame SM, Esteoulle L, Rich\u00e9 S, Margathe JF, Durroux T, Karpenko IA, Bonnet D.\u00a0Chemoselective Acylation of Hydrazinopeptides to Access Fluorescent Probes for Time-Resolved FRET Assays on GPCRs.<\/span><\/em>\u00a0Methods Mol Biol.<\/strong>\u00a02019;1947:137-147.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.\u00a0THE CONCISE GUIDE TO PHARMACOLOGY 2019\/20: G protein-coupled receptors.<\/span><\/em>\u00a0Br J Pharmacol.<\/strong>\u00a02019 Dec;176 Suppl 1(Suppl 1):S21-S141.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Heuninck J, Perpi\u00f1\u00e1 Viciano C, I\u015fbilir A, Caspar B, Capoferri D, Briddon SJ, Durroux T, Hill SJ, Lohse MJ, Milligan G, Pin JP, Hoffmann C.\u00a0Context-Dependent Signaling of CXC Chemokine Receptor 4 and Atypical Chemokine Receptor 3.<\/span><\/em>\u00a0Mol Pharmacol.<\/strong>\u00a02019 Dec;96(6):778-793.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Mendre C, Mouillac B.\u00a0Misfolding of vasopressin receptors: biased agonist pharmacochaperones as potential therapeutics.<\/span><\/em>\u00a0Adv Protein Chem Struct Biol.<\/strong>\u00a02019;118:249-272.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Heuninck J, Hounsou C, Dupuis E, Trinquet E, Mouillac B, Pin JP, Bonnet D, Durroux T.\u00a0Time-Resolved FRET-Based Assays to Characterize G Protein-Coupled Receptor Hetero-oligomer Pharmacology.<\/span><\/em>\u00a0Methods Mol Biol.<\/strong>\u00a02019;1947:151-168.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Jespersen NE, Leyrat C, G\u00e9rard FC, Bourhis JM, Blondel D, Jamin M, Barbar E.\u00a0The LC8-RavP ensemble Structure Evinces A Role for LC8 in Regulating Lyssavirus Polymerase Functionality.<\/span><\/em>\u00a0J Mol Biol.<\/strong>\u00a02019 Dec 6;431(24):4959-4977.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Boullet H, Bentot F, Hequet A, Ganem-Elbaz C, Bechara C, Pacreau E, Launay P, Sagan S, Jolivalt C, Lacombe C, Moumn\u00e9 R, Karoyan P.\u00a0Small AntiMicrobial Peptide With in Vivo Activity Against Sepsis.<\/span><\/em>\u00a0Molecules.<\/strong>\u00a02019 May 1;24(9):1702.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Vasiliauskait\u00e9-Brooks I, Healey RD, Granier S.\u00a07TM proteins are not necessarily GPCRs.<\/span><\/em>\u00a0Mol Cell Endocrinol.<\/strong>\u00a02019 Jul 1;491:110397.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Gauto DF, Estrozi LF, Schwieters CD, Effantin G, Macek P, Sounier R, Sivertsen AC, Schmidt E, Kerfah R, Mas G, Colletier JP, G\u00fcntert P, Favier A, Schoehn G, Schanda P, Boisbouvier J.\u00a0Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex.<\/span><\/em>\u00a0Nat Commun.<\/strong>\u00a02019 Jun 19;10(1):2697.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Allison TM, Bechara C.\u00a0Structural mass spectrometry comes of age: new insight into protein structure, function and interactions.<\/span><\/em>\u00a0Biochem Soc Trans.<\/strong>\u00a02019 Feb 28;47(1):317-327.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Schmidt V, Sidore M, Bechara C, Duneau JP, Sturgis JN.\u00a0The lipid environment of Escherichia coli Aquaporin Z.<\/span><\/em>\u00a0Biochim Biophys Acta Biomembr.<\/strong>\u00a02019 Feb 1;1861(2):431-440.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
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Belhocine A, Veglianese P, Hounsou C, Dupuis E, Acher F, Durroux T, Goudet C, Pin JP.\u00a0Profiling of orthosteric and allosteric group-III metabotropic glutamate receptor ligands on various G protein-coupled receptors with Tag-lite\u00ae<\/sup>\u00a0assays.<\/span><\/em>\u00a0<\/span>Neuropharmacology.<\/strong>\u00a02018 Sep 15;140:233-245.<\/span><\/p>\n<\/td>\n

PUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
M\u00f8ller TC, Hottin J, Clert\u00e9 C, Zwier JM, Durroux T, Rondard P, Pr\u00e9zeau L, Royer CA, Pin JP, Margeat E, Kniazeff J.\u00a0Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics.<\/span><\/em>\u00a0Sci Rep.<\/strong>\u00a02018 Jul 10;8(1):10414.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Hounsou C, Baehr C, Gasparik V, Alili D, Belhocine A, Rodriguez T, Dupuis E, Roux T, Mann A, Heissler D, Pin JP, Durroux T, Bonnet D, Hibert M.\u00a0From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled Receptors.<\/span><\/em>\u00a0J Med Chem.<\/strong>\u00a02018 Jan 11;61(1):174-188.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Vasiliauskait\u00e9-Brooks I, Healey RD, Rochaix P, Saint-Paul J, Sounier R, Grison C, Waltrich-Augusto T, Fortier M, Hoh F, Saied EM, Arenz C, Basu S, Leyrat C, Granier S.\u00a0Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.<\/span><\/em>\u00a0Nat Commun.<\/strong>\u00a02018 Dec 21;9(1):5437.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Berry L, Chen CT, Francia ME, Guerin A, Graindorge A, Saliou JM, Grandmougin M, Wein S, Bechara C, Morlon-Guyot J, Bordat Y, Gubbels MJ, Lebrun M, Dubremetz JF, Daher W.\u00a0Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny.<\/span><\/em>\u00a0Cell Mol Life Sci.<\/strong>\u00a02018 Dec;75(23):4417-4443.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Mouillac B, Mendre C.\u00a0Pharmacological Chaperones as Potential Therapeutic Strategies for Misfolded Mutant Vasopressin Receptors.<\/span><\/em>\u00a0Handb Exp Pharmacol.<\/strong>\u00a02018;245:63-83.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Perkovska S, M\u00e9jean C, Ayoub MA, Li J, Hemery F, Corbani M, Laguette N, Ventura MA, Orcel H, Durroux T, Mouillac B, Mendre C.\u00a0V1b<\/sub>\u00a0vasopressin receptor trafficking and signaling: Role of arrestins, G proteins and Src kinase.<\/span><\/em>\u00a0Traffic.<\/strong>\u00a02018 Jan;19(1):58-82.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Frantz MC, Pellissier LP, Pflimlin E, Loison S, Gand\u00eda J, Marsol C, Durroux T, Mouillac B, Becker JAJ, Le Merrer J, Valencia C, Villa P, Bonnet D, Hibert M.\u00a0LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism.<\/span><\/em>\u00a0J Med Chem.<\/strong>\u00a02018 Oct 11;61(19):8670-8692.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK.\u00a0Structure of the \u00b5-opioid receptor-Gi<\/sub>\u00a0protein complex.<\/span><\/em>\u00a0Nature.<\/strong>\u00a02018 Jun ;558(7711):547-552.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Gupta K, Li J, Liko I, Gault J, Bechara C, Wu D, Hopper JTS, Giles K, Benesch JLP, Robinson CV.\u00a0Identifying key membrane protein lipid interactions using mass spectrometry.<\/span><\/em>\u00a0Nat Protoc.<\/strong>\u00a02018 May;13(5):1106-1120.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Kurauskas V, Hessel A, Ma P, Lunetti P, Weinh\u00e4upl K, Imbert L, Brutscher B, King MS, Sounier R, Dolce V, Kunji ERS, Capobianco L, Chipot C, Dehez F, Bersch B, Schanda P.\u00a0How Detergent Impacts Membrane Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine.<\/span><\/em>\u00a0J Phys Chem Lett.<\/strong>\u00a02018 Mar 1;9(5):933-938.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Smith N, Pietrancosta N, Davidson S, Dutrieux J, Chauveau L, Cutolo P, Dy M, Scott-Algara D, Manoury B, Zirafi O, McCort-Tranchepain I, Durroux T, Bachelerie F, Schwartz O, M\u00fcnch J, Wack A, Nisole S, Herbeuval JP.\u00a0Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement.<\/span><\/em>\u00a0Nat Commun.<\/strong>\u00a02017 Feb 9;8:14253.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Recio R, Vengut-Climent E, Mouillac B, Orcel H, L\u00f3pez-L\u00e1zaro M, Calder\u00f3n-Monta\u00f1o JM, \u00c1lvarez E, Khiar N, Fern\u00e1ndez I.\u00a0Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification.<\/span><\/em>\u00a0Eur J Med Chem<\/strong>. 2017 Sep 29;138:644-660.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Moreno Delgado D, M\u00f8ller TC, Ster J, Giraldo J, Maurel D, Rovira X, Scholler P, Zwier JM, Perroy J, Durroux T, Trinquet E, Prezeau L, Rondard P, Pin JP.\u00a0Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.<\/span><\/em>\u00a0Elife.<\/strong>\u00a02017 Jun 29;6:e25233.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Ciolek J, Reinfrank H, Quinton L, Viengchareun S, Stura EA, Vera L, Sigismeau S, Mouillac B, Orcel H, Peigneur S, Tytgat J, Droctov\u00e9 L, Beau F, Nevoux J, Lomb\u00e8s M, Mourier G, De Pauw E, Servent D, Mendre C, Witzgall R, Gilles N.\u00a0Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease.<\/span><\/em>\u00a0Proc Natl Acad Sci U S A.<\/strong>\u00a02017 Jul 3;114(27):7154-7159.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Renner M, Paesen GC, Grison CM, Granier S, Grimes JM, Leyrat C.\u00a0Structural dissection of human metapneumovirus phosphoprotein using small angle x-ray scattering.<\/span><\/em>\u00a0Sci Rep.<\/strong>\u00a02017 Nov 1;7(1):14865.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Kurauskas V, Schanda P, Sounier R.\u00a0Methyl-Specific Isotope Labeling Strategies for NMR Studies of Membrane Proteins.<\/span><\/em>\u00a0Methods Mol Biol.<\/strong>\u00a02017;1635:109-123.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Vasiliauskait\u00e9-Brooks I, Sounier R, Rochaix P, Bellot G, Fortier M, Hoh F, De Colibus L, Bechara C, Saied EM, Arenz C, Leyrat C, Granier S.\u00a0Structural insights into adiponectin receptors suggest ceramidase activity.<\/span><\/em>\u00a0Nature.<\/strong>\u00a02017 Apr 6;544(7648):120-123.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Sounier R, Yang Y, Hagelberger J, Granier S, D\u00e9m\u00e9n\u00e9 H.\u00a01<\/sup>H,\u00a013<\/sup>C and\u00a015<\/sup>N backbone chemical shift assignments of camelid single-domain antibodies against active state \u00b5-opioid receptor.<\/span><\/em>\u00a0Biomol NMR Assign.<\/strong>\u00a02017 Apr;11(1):117-121.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Rossato M, Miralles G, M\u2019Kadmi C, Maingot M, Amblard M, Mouillac B, Gagne D, Martinez J, Subra G, Enjalbal C, Cantel S.\u00a0Quantitative MALDI-MS Binding Assays: An Alternative to Radiolabeling.<\/span><\/em>\u00a0ChemMedChem.<\/strong>\u00a02016 Dec 6;11(23):2582-2587.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Broad J, Maurel D, Kung VW, Hicks GA, Schemann M, Barnes MR, Kenakin TP, Granier S, Sanger GJ.\u00a0Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design.<\/span><\/em>\u00a0Sci Rep.<\/strong>\u00a02016 Aug 5;6:30797.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Damian M, Mary S, Maingot M, M\u2019Kadmi C, Gagne D, Leyris JP, Denoyelle S, Gaibelet G, Gavara L, Garcia de Souza Costa M, Perahia D, Trinquet E, Mouillac B, Galandrin S, Gal\u00e8s C, Fehrentz JA, Floquet N, Martinez J, Marie J, Ban\u00e8res JL.\u00a0Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.<\/span><\/em>\u00a0Proc Natl Acad Sci U S A.<\/strong>\u00a02015 Feb 3;112(5):1601-6.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Fern\u00e1ndez-Due\u00f1as V, Taura JJ, Cottet M, G\u00f3mez-Soler M, L\u00f3pez-Cano M, Ledent C, Watanabe M, Trinquet E, Pin JP, Luj\u00e1n R, Durroux T, Ciruela F.\u00a0Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats.<\/span><\/em>\u00a0Dis Model Mech.<\/strong>\u00a02015 Jan;8(1):57-63.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Levoye A, Zwier JM, Jaracz-Ros A, Klipfel L, Cottet M, Maurel D, Bdioui S, Balabanian K, Pr\u00e9zeau L, Trinquet E, Durroux T, Bachelerie F.\u00a0A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate.<\/span><\/em>\u00a0Front Endocrinol (Lausanne).<\/strong>\u00a02015 Nov 9;6:167.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Oueslati N, Hounsou C, Belhocine A, Rodriguez T, Dupuis E, Zwier JM, Trinquet E, Pin JP, Durroux T.\u00a0Time-resolved FRET strategy to screen GPCR ligand library.<\/span><\/em>\u00a0Methods Mol Biol.<\/strong>\u00a02015;1272:23-36.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Hounsou C, Margathe JF, Oueslati N, Belhocine A, Dupuis E, Thomas C, Mann A, Ilien B, Rognan D, Trinquet E, Hibert M, Pin JP, Bonnet D, Durroux T.\u00a0Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1\/D3 heterodimer.\u00a0<\/span><\/em>ACS Chem Biol.<\/strong>\u00a02015 Feb 20;10(2):466-74.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Blanc E, Wagner P, Plaisier F, Schmitt M, Durroux T, Bourguignon JJ, Partiseti M, Dupuis E, Bihel F.\u00a0Design and validation of a homogeneous time-resolved fluorescence cell-based assay targeting the ligand-gated ion channel 5-HT3A.<\/span><\/em>\u00a0Anal Biochem.<\/strong>\u00a02015 Sep 1;484:105-12.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Faklaris O, Cottet M, Falco A, Villier B, Laget M, Zwier JM, Trinquet E, Mouillac B, Pin JP, Durroux T.\u00a0Multicolor time-resolved F\u00f6rster resonance energy transfer microscopy reveals the impact of GPCR oligomerization on internalization processes.<\/span><\/em>\u00a0FASEB J.<\/strong>\u00a02015 Jun;29(6):2235-46.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n
Sounier R, Mas C, Steyaert J, Laeremans T, Manglik A, Huang W, Kobilka BK, D\u00e9m\u00e9n\u00e9 H, Granier S.\u00a0Propagation of conformational changes during \u03bc-opioid receptor activation.<\/span><\/em>\u00a0Nature.<\/strong>\u00a02015 Aug 20;524(7565):375-8.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n
Huang W, Manglik A, Venkatakrishnan AJ, Laeremans T, Feinberg EN, Sanborn AL, Kato HE, Livingston KE, Thorsen TS, Kling RC, Granier S, Gmeiner P, Husbands SM, Traynor JR, Weis WI, Steyaert J, Dror RO, Kobilka BK.\u00a0Structural insights into \u00b5-opioid receptor activation.<\/span><\/em>\u00a0Nature.<\/strong>\u00a02015 Aug 20;524(7565):315-21.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t2014 - 2010<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t
\n\n\n\n\n\n\n\n\n\n\n\n\n
Karpenko IA, Margathe JF, Rodriguez T, Pflimlin E, Dupuis E, Hibert M, Durroux T, Bonnet D.\u00a0Selective nonpeptidic fluorescent ligands for oxytocin receptor: design, synthesis, and application to time-resolved FRET binding assay.<\/span><\/em>\u00a0J Med Chem.<\/strong>\u00a02015 Mar 12;58(5):2547-52.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Karpenko IA, Kreder R, Valencia C, Villa P, Mendre C, Mouillac B, M\u00e9ly Y, Hibert M, Bonnet D, Klymchenko AS.\u00a0Red fluorescent turn-on ligands for imaging and quantifying G protein-coupled receptors in living cells.<\/span><\/em>\u00a0Chembiochem.<\/strong>\u00a02014 Feb 10;15(3):359-63.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Mary S, Damian M, Rahmeh R, Mouillac B, Marie J, Granier S, Ban\u00e8res JL.\u00a0Amphipols in G protein-coupled receptor pharmacology: what are they good for?<\/span><\/em>\u00a0J Membr Biol.<\/strong>\u00a02014 Oct;247(9-10):853-60.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Rahmeh R, Damian M, Cottet M, Orcel H, Mendre C, Durroux T, Sharma KS, Durand G, Pucci B, Trinquet E, Zwier JM, Deupi X, Bron P, Ban\u00e8res JL, Mouillac B, Granier S.\u00a0Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy.<\/span><\/em>\u00a0Proc Natl Acad Sci U S A.<\/strong>\u00a02012 Apr 24;109(17):6733-8. PMC3340029.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, Granier S.\u00a0Crystal structure of the \u00b5-opioid receptor bound to a morphinan antagonist.<\/span><\/em>\u00a0Nature<\/strong>. 2012 Mar 21;485(7398):321-6.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Granier S, Manglik A, Kruse AC, Kobilka TS, Thian FS, Weis WI, Kobilka BK.\u00a0Structure of the \u03b4-opioid receptor bound to naltrindole.<\/span><\/em>\u00a0Nature<\/strong>. 2012 May 16;485(7398):400-4.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Granier S, Kobilka B.\u00a0A new era of GPCR structural and chemical biology.<\/span><\/em>\u00a0Nat Chem Biol.<\/strong>\u00a02012 Jul 18;8(8):670-3.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Granier S.\u00a0Structure of mu and delta opioid receptors.<\/span><\/em>\u00a0Med Sci (Paris)<\/strong>. 2012 Oct;28(10):870-5.<\/span><\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
El Moustaine D, Granier S, Doumazane E, Scholler P, Rahmeh R, Bron P, Mouillac B, Ban\u00e8res JL, Rondard P, Pin JP.\u00a0Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling.<\/span><\/em>\u00a0Proc Natl Acad Sci U S A<\/strong>. 2012 Oct 2;109(40):16342-7.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n
Cottet M, Albizu L, Perkovska S, Jean-Alphonse F, Rahmeh R, Orcel H, M\u00e9jean C, Granier S, Mendre C, Mouillac B, Durroux T.\u00a0Past, present and future of vasopressin and oxytocin receptor oligomers, prototypical GPCR models to study dimerization processes.<\/span><\/em>\u00a0Curr Opin Pharmacol.<\/strong>\u00a02010 Feb;10(1):59-66.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n
Arcemisb\u00e9h\u00e8re L, Sen T, Boudier L, Balestre MN, Gaibelet G, Detouillon E, Orcel H, Mendre C, Rahmeh R, Granier S, Viv\u00e8s C, Fieschi F, Damian M, Durroux T, Ban\u00e8res JL, Mouillac B.\u00a0Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimers.<\/span><\/em>\u00a0J Biol Chem.<\/strong>\u00a02010 Feb 26;285(9):6337-47.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t2009 -<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t
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Granier S, Kim S, Fung JJ, Bokoch MP, Parnot C.\u00a0FRET-based measurement of GPCR conformational changes.<\/span><\/em>\u00a0Methods Mol Biol.<\/strong>\u00a02009;552:253-68.<\/span><\/td>\nPUBMED<\/a><\/span><\/td>\n<\/tr>\n
Bellot G, Granier S, Bourguet W, Seyer R, Rahmeh R, Mouillac B, Pascal R, Mendre C, D\u00e9m\u00e9n\u00e9 H.\u00a0Structure of the third intracellular loop of the vasopressin V2 receptor and conformational changes upon binding to gC1qR.<\/span><\/em>\u00a0J\u00a0Mol Biol.<\/strong>\u00a02009 May 8;388(3):491-507.<\/span><\/td>\nPUBMED<\/a><\/span><\/td>\n<\/tr>\n
Richter W, Day P, Agrawal R, Bruss MD, Granier S, Wang YL, Rasmussen SG, Horner K, Wang P, Lei T, Patterson AJ, Kobilka B, Conti M.\u00a0Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4.<\/span><\/em>\u00a0EMBO J.<\/strong>\u00a02008 Jan 23;27(2):384-93.<\/span><\/td>\nPUBMED<\/a><\/span><\/td>\n<\/tr>\n
Granier S, Jean-Alphonse F, Bacqueville D, Monteil A, Pascal R, Poncet J, Guillon G, Boudier L, Arcemisb\u00e9h\u00e8re L, Mouillac B, Bellot G, D\u00e9m\u00e9n\u00e9 H, Mendre C.\u00a0The multifunctional protein GC1q-R interacts specifically with the i3 loop arginine cluster of the vasopressin V2 receptor.<\/span><\/em>\u00a0Regul Pept.<\/strong>\u00a02008 Jun 5;148(1-3):76-87.<\/span><\/td>\nPUBMED<\/a><\/span><\/td>\n<\/tr>\n
Huang B, Wu H, Bhaya D, Grossman A, Granier S, Kobilka BK, Zare RN.\u00a0Counting low-copy number proteins in a single cell<\/span><\/em>.\u00a0Science<\/strong>. 2007 Jan 5;315(5808):81-4.<\/span><\/td>\nPUBMED<\/span><\/a><\/td>\n<\/tr>\n
Granier S, Kim S, Shafer AM, Ratnala VR, Fung JJ, Zare RN, Kobilka B.\u00a0Structure and conformational changes in the C-terminal domain of the beta2-adrenoceptor: insights from fluorescence resonance energy transfer studies.<\/span><\/em>\u00a0J Biol Chem.<\/strong>\u00a02007 May 4;282(18):13895-905.<\/span><\/td>\nPUBMED<\/a>\u00a0<\/td>\n<\/tr>\n
Granier S, Jean-Alphonse F, D\u00e9m\u00e9n\u00e9 H, Guillon G, Pascal R, Mendre C.\u00a0Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs.<\/span><\/em>\u00a0Bioorg Med Chem Lett.<\/strong>\u00a02006 Feb;16(3):521-4.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n
Granier S, Terrillon S, Pascal R, D\u00e9m\u00e9n\u00e9 H, Bouvier M, Guillon G, Mendre C.\u00a0A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein.<\/em><\/span>\u00a0J Biol Chem.<\/strong>\u00a02004 Dec 3;279(49):50904-14.<\/span><\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n
D\u00e9m\u00e9n\u00e9 H, Granier S, Muller D, Guillon G, Dufour MN, Delsuc MA, Hibert M, Pascal R, Mendre C.\u00a0<\/span>Active peptidic mimics of the second intracellular loop of the V(1A) vasopressin receptor are structurally related to the second intracellular rhodopsin loop: a combined 1H NMR and biochemical study.<\/span><\/em> Biochemistry<\/span><\/strong>.<\/strong> 2003 Jul 15;42(27):8204-13.<\/span><\/td>\nPUBMED<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

2025 Cannone G, Berto L, Malhaire F, Ferguson G, Fouillen A, Balor S, Font-Ingles J, Llebaria A, Goudet C, Kotecha A, K R V, Lebon G. Conformational diversity in class C GPCR positive allosteric modulation. Nat Commun. 2025 Jan 13;16(1):619. doi: 10.1038\/s41467-024-55439-9. PUBMED 2024 – 2020 Ribeiro EA Jr, Leyrat C, G\u00e9rard FCA, Jamin M. Lire plus …<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-73","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=\/wp\/v2\/pages\/73","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=73"}],"version-history":[{"count":167,"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=\/wp\/v2\/pages\/73\/revisions"}],"predecessor-version":[{"id":2104,"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=\/wp\/v2\/pages\/73\/revisions\/2104"}],"wp:attachment":[{"href":"https:\/\/granier-mouillac-lab.igf.cnrs.fr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=73"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}